Recently, my daughter ,Rebekah, in Ft. Myers, FL asked me about using propolis for MRSA.  She has a friend who has been told she has MRSA infection in her sinuses.  I  jumped online to find any studies on this topic, knowing that propolis has been proven through research to be effective against MRSA strains of Staphylococcus.  My go-to source is the National Institutes of Health,

A study at the University of Heidelberg tested a propolis extract against a variety of disease-causing bacteria, including MRSA, vancomycin-resistant Enterococcus faecium (VRE), Candida albicans, and Streptococcus pyogenes.

Within six hours, propolis stopped the activity of S. pyogenes, the cause of strep throat and hard-to-stop skin infections. The study also found that it had a high degree of antibacterial activity against all tested MRSA strains, and inhibited Candida (Yeast Infection, Athlete’s Foot) as well.

Raw Propolis drying before extraction

From the Article: Evaluation of the in vitro antimicrobial activity of an ethanol extract of Brazilian classified propolis on strains of Staphylococcus aureus 

In an  In vitro study (meaning in a test tube or petri dish), researchers set out to find the minimum strength of propolis  that would inhibit the MSSA and MRSA germs of Staph. They found that 1.5% strength propolis in ethanol (distilled alcohol, like vodka or brandy)  killed MSSA and MRSA bacteria

The measurement they noted was 1420 ug/ml,  which is 1420 micrograms (weight) of propolis in 1 millilitre (volume) of ethanol.  I found the weight of 1 millilitre of ethanol so I could divide the weight of propolis into the weight of the ethanol.  I also found an online converter that gives percentages for ug/ml measurements.

We make 10% and 30% tincture, and put 2.5% propolis in our BEE Rescue Cream.


From the article: Antibacterial activity of propolis against MRSA and synergism with topical mupirocin.

The aim of the present study was to investigate the activity of the propolis and its combinations with mupirocin against methicillin-resistant Staphylococcus aureus (MRSA) in nasal carriage.

This study was carried out between June and August 2005. Propolis was used in the nasal passages of rabbits with MRSA infection in the nose. Group 1 was treated with topical mupirocin + ethanolic extract of propolis drops. Group 2 received topical mupirocin, only. Group 3 was administered ethanolic extract of propolis drops, only and the control group (group 4) was only treated with phosphate-buffered solution drops for 7 days.  The numbers of bacteria in group 1  who were administerd both the propolius extract and mupirocin antibiotic were determined to be significantly lower than in the other groups.

The propolis extract addition to mupirocin regimen was found to result in more profound reduction in bacterial cell count and inflammatory response compared with the rest of the treatment modalities.


In this article: Antimicrobial Activities of European Propolis Collected from Various Geographic Origins Alone and in Combination with Antibiotics.

Scientists tested propolis extract on gram negative and gram positive bacteria including MRSA and VRE (Vancomycin-resistant Enterococcus) All propolis samples showed moderate antibacterial effect against Gram-positive microorganisms with  ranging from  .8% – 2.5% strength propolis extract. Propolis extract showed  moderate activity against Gram-negative bacteria with .5% to 5% strength propolis extract) It also displayed moderate antifungal activity with .5% – 2.5% strength propolis extract. They also tested propolis extract given along with other antibiotics and found synergistic (means together, they enhance the work of each other) interactions against drug-resistant microbial pathogens including MRSA and VRE. Conclusions: The propolis extract synergistically enhanced the efficacy (positive results) of antibiotics.


 In the article: Susceptibility of Staphylococcus aureus clinical isolates to propolis extract alone or in combination with antimicrobial drugs.

Ethanol extract of Propolis displayed  effectiveness against twelve Stapholococcus. aureus strains, with strenghts of .78% to 3.1% propolis extract.


From the article:  Agents for the decolonization of methicillin-resistant Staphylococcus aureus.

This  article is from and not specifically about propolis, but  about the different avenues one should take to get rid of systemic MRSA  – nasal treatments, topical treatments, washing skin with antibacterial soaps.

“The most extensive research in MRSA decolonization has been conducted with mupirocin, which is applied to the nares (nasal passages) 2-3 times/day for 5 days.  If total body decolonization is necessary, bathing or showering with an antiseptic agent such as chlorhexidine gluconate is recommended in combination with the nasal treatment.  Homeopathic and investigational agents may also be effective. Although mupirocin is the standard of care for decolonization of MRSA, several agents demonstrate efficacy and many merit further investigation.”

Propolis IS one of these investigational agents that has demonstrated  could be used this way, too. Propolis Oil and Tincture can be taken orally, or used on skin, as can the BEE Rescue Cream.  Propolis Nasal spray can be used in the nose.


Propolis for MRSA – Health ~ Powered by BEES!

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